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Published TCIMAIL newest issue No.197
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CAS RN: 101968-85-8 | Product Number: B5324
N-tert-Butylcarbamoyl-L-tert-leucine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-2-[3-(tert-Butyl)ureido]-3,3-dimethylbutyric Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€59.00
|
1 | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B5324 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__2__2N__2O__3 = 230.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 101968-85-8 |
| Reaxys Registry Number | 14336343 |
| PubChem Substance ID | 354334535 |
| MDL Number | MFCD12796012 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 182 °C(dec.) |
| Specific Rotation | -6° (C=1,AcOH) |
GHS
Related Laws:
Transport Information:
| HS Number | 2924190090 |
Application
A Synthetic Intermediate of Peptidic Protease Inhibitor
This product is used as a synthetic intermediate of peptidic protease inhibitor for the potential treatment of hepatic virus infection, such as boceprevir.
References
- Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection
- Synthesis and Process Optimization of Boceprevir: A Protease Inhibitor Drug
PubMed Literature
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