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Published TCIMAIL newest issue No.197
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CAS RN: 130525-58-5 | Product Number: A3442
Zanamivir Azide Triacetate Methyl Ester
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Purity: >95.0%(HPLC)
Synonyms:
- (1S,2R)-1-[(2R,3R,4S)-3-Acetamido-4-azido-6-(methoxycarbonyl)-3,4-dihydro-2H-pyran-2-yl]propane-1,2,3-triyl Triacetate
- D-Glycero-D-galacto-non-2-enonic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€135.00
|
Contact Us | 19 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A3442 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__4N__4O__1__0 = 456.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 130525-58-5 |
| Reaxys Registry Number | 4359783 |
| PubChem Substance ID | 468590302 |
| MDL Number | MFCD08704809 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 90.0 to 94.0 °C |
| Specific rotation | +102 to +108 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 91 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2932990090 |
Application
A Key Synthetic Intermediate of Zanamivir and its Analogs
This product has been used as a key synthetic intermediate of zanamivir [Z0023] which is an influenza virus neuraminidase inhibitor, and its analogs.
References
- The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor
- Synthesis of the potent influenza neuraminidase inhibitor 4-guanidino Neu5Ac2en. X-ray molecular structure of 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-erythro-L-gluco-nonionic acid
- Syntheses of triazole-modified zanamivir analogs via click chemistry and anti-AIV activities
Product Documents (Note: Some products will not have analytical charts available.)
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