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CAS RN: 5508-58-7 | Product Number: A2459
Andrographolide
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€44.00
|
2 | 37 |
|
| 5G |
€140.00
|
1 | 24 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2459 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__0O__5 = 350.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 5508-58-7 |
| Reaxys Registry Number | 5609598 |
| PubChem Substance ID | 253659551 |
| Merck Index (14) | 633 |
| MDL Number | MFCD07778082 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -124 to -129 deg(C=1.5, AcOH) |
Properties (reference)
| Melting Point | 231 °C |
| Specific Rotation | -126° (C=1.5,AcOH) |
| Maximum Absorption Wavelength | 223(MeOH) nm |
GHS
Related Laws:
| EC Number | 226-852-5 |
| RTECS# | LU3490750 |
Transport Information:
| HS Number | 2932209090 |
Application
Studies on the Pharmacological Activity of Andrographolide as a NF-κB Activation Inhibitor and an Anti-inflammatory Agent
References
- Immunostimulant agents from Andrographis paniculata
- Andrographolide Attenuates Inflammation by Inhibition of NF-κB Activation through Covalent Modification of Reduced Cysteine 62 of p50
- Y.-F. Xia, B.-Q. Ye, Y.-D. Li, J.-G. Wang, X.-J. He, X. Lin, X. Yao, D. Ma, A. Slungaard, R. P. Hebbel, N. S. Key, J.-G. Geng, J. Immunol. 2004, 173, 4207.
- Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti- inflammatory effect
- In vitro and in vivo anti-inflammatory effects of andrographolide
- Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
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