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Published TCIMAIL newest issue No.197
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CAS RN: 154-93-8 | Product Number: C2634
Carmustine
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Purity: >98.0%(HPLC)
Synonyms:
- 1,3-Bis(2-chloroethyl)-1-nitrosourea
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€126.00
|
6 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C2634 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__5H__9Cl__2N__3O__2 = 214.05 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 154-93-8 |
| Reaxys Registry Number | 2049744 |
| PubChem Substance ID | 160871393 |
| Merck Index (14) | 1845 |
| MDL Number | MFCD00057706 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(UV-vis method) | min. 95.0 % |
Properties (reference)
| Melting Point | 32 °C |
| Degree of solubility in water | 4 g/l 25 °C |
| Solubility (soluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. H360 : May damage fertility or the unborn child. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H341 : Suspected of causing genetic defects. H350 : May cause cancer. |
| Precautionary Statements | P260 : Do not breathe dust. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 205-838-2 |
| RTECS# | YS2625000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2924190090 |
Application
Cancer Research
References
- Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain
- L. K. Fung, M. G. Ewend, A. Sills, E. P. Sipos, R. Thompson, M. Watts, O. M. Colvin, H. Brem, W. M. Saltzman, Cancer Res. 1998, 58, 672.
- Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo
- T. Moritz, W. Mackay, B. J. Glassner, D. A. Williams, L. Samson, Cancer Res. 1995, 55, 2608.
- Biodegradable polymer implants to treat brain tumors
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