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Published TCIMAIL newest issue No.197
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CAS RN: 53164-05-9 | Product Number: A2452
Acemetacin
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Purity: >98.0%(GC)(T)
Synonyms:
- [1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetoxyacetic Acid
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic Acid Carboxymethyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€25.00
|
1 | 3 |
|
| 5G |
€79.00
|
1 | 1 |
|
| 25G |
€269.00
|
1 | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2452 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__1H__1__8ClNO__6 = 415.83 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 53164-05-9 |
| Reaxys Registry Number | 501672 |
| PubChem Substance ID | 135727247 |
| Merck Index (14) | 27 |
| MDL Number | MFCD00151473 |
Specifications
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 151.0 to 154.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 152 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 258-403-4 |
| RTECS# | NL3521400 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2933998090 |
Application
HPLC Labeling Reagent for Amines
References
- Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts
- Enhancement of chemotherapeutic drug toxicity to human tumor cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)
- Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety
- Pharmacodynamics of acemetacin
- H. Jacobi, H. D. Dell, Arzneim.-Forsch. 1980, 30, 1348.
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