Hemagglutinin: Recombinant Lectins

Lectin, well known as hemagglutinin, is widely distributed in plants, fungi like mushrooms, and animals. It has been used as a versatile tool in the glycoscience and cell research fields for a long time. TCI has a lineup of recombinant lectins whose genes have been cloned because they provide more stable quality rather than extract ones (1-6).
The glycan structure and expression level on the surface of erythrocytes are diverse depending on the animals (see below figure), and the profiling of hemagglutination caused by lectins is different. As other applications of lectin reagents, they have been utilized in lectin-staining of tissues, mitogens, cell profiling, prognosis with glyco-biomarker, and signal induction of cells and so on.

1-5 and 6 were commercialized under licenses from National Institute of Advanced Industrial Science and Technology (AIST) and Gekkeikan Sake Company, LTD., respectively.

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