Monoclonal Antibody (LY111) Recognizing Chondroitin Sulfate A

The monoclonal antibody 1 binds to chondroitin sulfate A, a type of glycosaminoglycan. It has been reported that chondroitin sulfates are ubiquitous in various tissues such as cartilage, cornea, and brain, and are involved in moisture regulation and cell adhesion, as well the immune system. 1 preferentially recognizes chondroitin sulfate A, which bares a sulfate at 4-position of GalNAc (2).¹⁾

Chondroitin Sulfate A (2)