用于脂滴染色的荧光染料ShoyakuGreen

脂滴 (LDs)是储存中性脂的细胞器，主要由甘油三酯和胆固醇酯组成。很多细胞中都含有脂滴，据报道脂滴的作用还涉及到生物学功能^1-3)。Karasawa等人开发的ShoyakuGreen是一种可以特异性染色脂滴的荧光探针⁴⁾。在激发波长403 nm和发射波长525 nm处可以分别观察到脂滴上ShoyakuGreen的荧光信号。即使以高浓度添加到培养基中，ShoyakuGreen也表现出低细胞毒性，因此它对培养细胞的脂滴染色很有用⁴⁾。

关键词

T3935

ShoyakuGreen (=TFMAQ-8Ph)

N0659

尼罗红

P2891

PC 6S (2mg/mL于二甲亚砜中) [用于生化研究]

O0483

油红O [用于生化研究]

相关产品分类页

• 脂滴用荧光染色剂

文献

• 1) Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse
  • T. Tatsumi, K. Takayama, S. Ishii, A. Yamamoto, T. Hara, N. Minami, N. Miyasaka, T. Kubota, A. Matsuura, E. Itakura, S. Tsukamoto, Development 2018, 145, dev161893.
• 2) An Overview of Lipid Droplets in Cancer and Cancer Stem Cells
  • L. Tirinato, F. Pagliari, T. Limongi, M. Marini, A. Falqui, J. Seco, P. Candeloro, C. Liberale, E. Di Fabrizio, Stem Cells Int. 2017, 1656053.
• 3) The lipid droplet is an important organelle for hepatitis C virus production
  • Y. Miyanari, K. Atsuzawa, N. Usuda, K. Watashi, T. Hishiki, M. Zayas, R. Bartenschlager, T. Wakita, M. Hijikata, K. Shimotohno, Nat. Cell Biol. 2007, 9, 1089.
• 4) Selective synthesis of substituted amino-quinoline derivatives by C-H activation and fluorescence evaluation of their lipophilicity-responsive properties
  • Y. Fuchi, M. Sakuma, K. Ohyama, R. Hagihara, M. Kohno, K. Hamada, A. Mizutani, S. Karasawa, Sci. Rep. 2019, 9, 17723.

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