轻松扫码查看产品文档 | TCIMAIL No.196 已上新 | TCI试剂——品质可靠,值得信赖
订购方法?联系方式:021-67121386 / Sales-CN@TCIchemicals.com
Maximum quantity allowed is 999
请选择数量
Transformation of Aldehydes and Ketones into Homologous Carboxylic Acids
Krohn et al. have reported the transformation reaction of several aldehydes and ketones into carboxylic acids using the 1-oxide derivative introduced from 2-trimethylsilyl-1,3-dithiane. According to their results, the intermediate ketene dithioacetals are hydrolyzed in acidic acetonitrile to give the corresponding homologous carboxylic acids in good yields. The one-carbon homologation reaction is an important transformation in organic synthesis, and therefore various applications using their methodology also can be fully expected.