Virus-related Glycan Epitopes（Virus-related Oligosaccharides） | 梯希爱(上海)化成工业发展有限公司

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Virus-oligosaccharide relationship

When a virus infects mammalian host cells, glycan epitopes on the cell surface is exploited as a virus receptor. And the surface of a virus particle is frequently modified with glycosylation in order to escape from an immunological host defense. For studies of virus-glycan interaction and infectious inhibition, we show a lineup of oligosaccharide products containing virus-related glycan epitope structures.

Virus-oligosaccharide relationship

Virus-related terminal epitopes of oligosaccharide

Virus-related terminal epitopes of oligosaccharide

Reference

Virus recognition of glycan receptors
- A. J. Thompson, R. P. de Vries, J. C. Paulson, Curr. Opin. Virol. 2019, 34, 117.

Oligosaccharides containing virus-related glycan epitopes

【Siaα2-3Galβ1-3GalNAc】

–––––: SSEA-4

【Siaα2-3Galβ1-4GlcNAc】

N0854: Neu5Acα(2-3)Galβ(1-4)GlcNAc-β-pNP
S0910: Sialyl Neolactotetraosylceramide (=Sialyl nLc₄Cer)
–––––: Neu5Acα(2-3)Galβ(1-4)GlcNAc-β-propylamine

【Siaα2-6Galβ1-4GlcNAc】

S0523: Sialylglycopeptide (SGP)
D4065: Disialyloctasaccharide
N1065: Neu5Acα(2-6) N-Glycan
N0913: Disialylnonasaccharide-β-pNP
D4217: Disialylnonasaccharide-β-ethylazide
N0950: Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-ethylamine
N0856: Neu5Acα(2-6)Galβ(1-4)GlcNAc-β-pNP
N1117: Neu5Acα(2-6)Galβ(1-4)GlcNAcβ(1-3)Galβ(1-4)GlcNAc-β-propylamine
N1118: Neu5Acα(2-6)Galβ(1-4)GlcNAcβ(1-3)Galβ(1-4)GlcNAcβ(1-3)Galβ(1-4)GlcNAc-β-propylamine

【9-OAcSiaαGal】

A3414: N-Acetyl-9-O-acetylneuraminic Acid
A3415: N-Acetyl-9-deoxy-9-acetamidoneuraminic Acid
–––––: 9OAc-Neu5Acα(2-3)Galβ(1-4)Glc
–––––: 9OAc-Neu5Acα(2-6)Galβ(1-4)Glc

【(Galβ1-4GlcNAc)_n】

G0515: L1-L1-β-PEG₃-biotin
–––––: LacNAc 2mer (L1-L1)
–––––: LacNAc 4mer (L1-L1-L1-L1)

【Galβ1-4(α1-3Fuc)GlcNAc】

S0946: SSEA-1-PrNH₂
H1719: HSA-Lewis X

【GalNAcα1-3(α1-2Fuc)Galβ】

A2631: A Antigen PEG-trifluoroacetamide
–––––: Trisaccharide (Blood-type A Antigen) PEG-resin
–––––: Blood-type A Antigen propylamine

【Galα1-3(α1-2Fuc)Galβ】

B4172: B Antigen PEG-trifluoroacetamide
–––––: Trisaccharide (Blood-type B Antigen) PEG-resin
–––––: Blood-type B Antigen propylamine

【GalNAcβ1-3Galα1-4Gal】

G0354: GalNAcβ(1-3)Galα(1-4)Galβ(1-4)Glc-β-pNP
–––––: Gb₄-PrNH₂
G0580: Gb₄-Ceramide

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Virus-related Glycan Epitopes (Virus-related Oligosaccharides) (PDF)

Related Product Category Page

Infectious Disease Research [Application Using Glyco-materials]