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Published TCIMAIL newest issue No.197
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CAS RN: 60-70-8 | Product Number: V0148
Veratramine
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
€31.00
|
1 | Contact Us |
|
| 50MG |
€101.00
|
1 | 3 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | V0148 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__3__9NO__2 = 409.61 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 60-70-8 |
| Reaxys Registry Number | 55515 |
| PubChem Substance ID | 354335607 |
| Merck Index (14) | 9952 |
| MDL Number | MFCD00468124 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 208.0 to 212.0 °C |
| Specific rotation [a]20/D | -64.0 to -68.0 deg(C=0.5, CHCL3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C |
| Specific Rotation | -66° (C=0.5,CHCl3) |
| Maximum Absorption Wavelength | 268 nm |
| Solubility in water | Slightly soluble |
| Solubility (soluble in) | Alcohol, Methanol, Benzene, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | YX5094000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939800000 |
Application
Veratramine: A Steroidal Alkaloid with Some Bioactivities
Veratramine is a major lipid-soluble steroidal alkaloid existing in Veratrum nigrum L., belongs to the family liliaceae, which is a traditional medicinal plant in China. Veratramine has been reported to teratogenic, anti-tumor and anti-hypertension effects. (The product is for research purpose only.)
References
- The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic hedgehog signal transduction
- Steroidal alkaloids from the roots and rhizomes of Veratrum nigrum L.
- Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats
- Antitumor and antiplatelet activity of alkaloids from Veratrum dahuricum
- The Veratrum and Solanum alkaloids (a review)
- Metabolism study of veratramine associated with neurotoxicity by using HPLC-MSn
- Identification and characterization of in vitro and in vivo metabolites of steroidal alkaloid veratramine
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