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CAS RN: 674773-07-0 | Product Number: S0938
Strontium Ranelate Hydrate
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Purity: >97.0%(T)
Synonyms:
- Ranelic Acid Strontium Salt Hydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
44,00 €
|
5 | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0938 |
| Purity / Analysis Method | >97.0%(T) |
| Molecular Formula / Molecular Weight | C__1__2H__6N__2O__8SSr__2·xH__2O = 513.49 (as Anhydrous) |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 674773-07-0 |
| Related CAS RN | 135459-87-9 |
| Reaxys Registry Number | 10746913 |
| PubChem Substance ID | 253660598 |
| Merck Index (14) | 8106 |
| MDL Number | MFCD09038742 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 97.0 %(calcd.on anh.substance) |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
| RTECS# | XM7581000 |
Transport Information:
| HS Number | 2934999090 |
Application
Strontium Ranelate: A Compound with a Dual Mode of Action Optimizing Bone Formation and Resorption
Strontium ranelate (S12911) is composed of an organic moiety (ranelic acid) and of two atoms of stable non-radioactive strontium. In vitro, strontium ranelate increases collagen and noncollagenic proteins synthesis by mature osteoblast enriched cells. Strontium ranelate decreases bone resorption and increases bone formation, resulting in increased bone mass. Therefore, it is called as a “dual action bone agent" (DABA).
References
- An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats
- The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro
- Incorporation and distribution of strontium in bone (a review)
- The biological role of strontium (a review)
- Strontium ranelate: New insights into its dual mode of action (a review)
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