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Published TCIMAIL newest issue No.197
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CAS RN: 4759-48-2 | Product Number: R0088
13-cis-Retinoic Acid
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Purity: >97.0%(T)(HPLC)
Synonyms:
- (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
- Isotretinoin
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
27,00 €
|
2 | 6 |
|
| 1G |
173,00 €
|
1 | 36 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0088 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__8O__2 = 300.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 4759-48-2 |
| Reaxys Registry Number | 1885770 |
| PubChem Substance ID | 135727087 |
| Merck Index (14) | 5228 |
| MDL Number | MFCD00079542 |
Specifications
| Appearance | Orange to Brown powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
Properties (reference)
| Melting Point | 175 °C |
| Maximum Absorption Wavelength | 354(EtOH) nm |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Alcohol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H360 : May damage fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. |
Related Laws:
| EC Number | 225-296-0 |
| RTECS# | VH6440000 |
Transport Information:
| HS Number | 2936210000 |
Application
Studies of Biological Actions
References
- Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid
- Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids
- Effects of all-trans-retinoic acid and 13-cis-retinoic acid on breast-cancer cell lines: growth inhibition and apoptosis induction
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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