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CAS RN: 65-86-1 | Product Number: O0633
Orotic Acid
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Purity: >95.0%(T)(HPLC)
Synonyms:
- 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic Acid
- 6-Carboxyuracil
- Uracil-6-carboxylic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€60.00
|
1 | 31 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0633 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__5H__4N__2O__4 = 156.10 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Moisture Sensitive |
| CAS RN | 65-86-1 |
| Reaxys Registry Number | 383901 |
| MDL Number | MFCD00006027 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 345 °C |
| Degree of solubility in water | 1.82 g/l |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H335 : May cause respiratory irritation. |
| Precautionary Statements | P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
| EC Number | 200-619-8 |
| RTECS# | RM3180000 |
Transport Information:
| HS Number | 2933599590 |
Application
Orotic Acid: An Essential Intermediate in the Biosynthesis of Pyrimidine Nucleotides
Orotic acid is known to be an essential intermediate in the biosynthesis of pyrimidine nucleotides. In mammals, it is released from mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to uridine monophosphate (UMP) by the cytoplasmic enzyme UMP synthase. Urinary orotic acid determination is a useful screening tool for many inborn errors of the urea cycle and a number of other disorders.
Reference
- Orotic acid, more than just an intermediate of pyrimidine de novo synthesis
- Orotate (orotic acid): An essential and versatile molecule
- Orotic acid excretion and arginine metabolism
Product Documents (Note: Some products will not have analytical charts available.)
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