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Published TCIMAIL newest issue No.197
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CAS RN: 82571-53-7 | Product Number: O0610
Ozagrel
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic Acid
- (E)-3-[4-[(1H-Imidazol-1-yl)methyl]phenyl]acrylic Acid
- (E)-4-(1-Imidazolylmethyl)cinnamic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
78,00 €
|
Contact Us | 21 |
|
| 5G |
170,00 €
|
Contact Us | 26 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0610 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__2N__2O__2 = 228.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 82571-53-7 |
| Reaxys Registry Number | 5269808 |
| MDL Number | MFCD00868231 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 223.0 to 227.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 225 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2933299090 |
Application
Ozagrel: A Selective Thromboxane A2 (TXA2) Synthetase Inhibitor
Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets during hemostasis, and also is a potent constrictor of smooth muscle. Ozagrel (OKY-046) is a selective TXA2 synthetase inhibitor, and blocks platelet aggregation and reduces hypersensitivity of the bronchial muscles. In clinical, it has been used for the treatment of a therapeutic agent for ischemic heart diseases, thromboembolic disorders, cerebral circulatory disorders, and asthma. (The product is for research purpose only.)
References
- Pharmacological studies on the TXA synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046)
- Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets
- Thromboxane A2 inhibition: Therapeutic potential in bronchial asthma (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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