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CAS RN: 5868-05-3 | Product Number: N0974
Niceritrol
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- Pentaerythritol Tetranicotinate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€129.00
|
1 | 14 |
|
| 100MG |
€387.00
|
1 | 6 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N0974 |
| Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__9H__2__4N__4O__8 = 556.53 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 5868-05-3 |
| Reaxys Registry Number | 377170 |
| PubChem Substance ID | 354333980 |
| Merck Index (14) | 6497 |
| MDL Number | MFCD00215982 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 162.0 to 166.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 165 °C |
GHS
Related Laws:
| EC Number | 227-519-7 |
| RTECS# | QT1980000 |
Transport Information:
| HS Number | 2933399990 |
Application
血漿中脂質を低下し，末梢血管を拡張する化合物，ニセリトロール
Niceritrol is an ester of nicotinic acid [N0082] that suppresses free fatty acid (FFA) release from fat cells, and thereby lowers cholesterol and triglycerides in total plasma. Niceritrol also has peripheral tissue vasodilatory activity, and some studies suggest that niceritrol increases prostaglandin formation. In addition, niceritrol might be cause of hypophosphatemic action and thrombocytopenia and anemia, but the mechanisms of the actions are still unclear. (The product is for research purpose only.)
References
- Actions of vitamins A and E and some nicotinic acid derivatives on plasma lipids and on lipid infiltration of aorta in cholesterol-fed rabbits
- Effect of niceritrol on streptozocin-induced diabetic neuropathy in rats
- Effects of niceritrol on fecal and urinary phosphate excretion in normal rats
- Thrombocytopenia and Anemia Induced by Niceritrol Used for Amelioration of Hyperphosphatemia in a Hemodialysis Patient
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