Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 122647-32-9 | Product Number: I0946
Ibutilide Hemifumarate
×
![]()
×
Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 20MG |
€58.00
|
3 | Contact Us |
|
| 100MG |
€221.00
|
Contact Us | 1 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | I0946 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__0H__3__6N__2O__3S·^^1/__2C__4H__4O__4 = 442.62 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 122647-32-9 |
| Related CAS RN | 122647-31-8 |
| PubChem Substance ID | 253662069 |
| Merck Index (14) | 4883 |
| MDL Number | MFCD01715410 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Maximum Absorption Wavelength | 267(EtOH) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | PB0475700 |
Transport Information:
| HS Number | 2935909099 |
Application
Ibutilide Fumarate: The First "Pure" Class III Antiarrhythmic Agent
Ibutilide fumarate, the first "pure" class III antiarrhythmic agent, is shown to increase the refractory period and action potential duration of myocardial cells. At a cellular level, ibutilide fumarate exerts two main actions: dihydropyridine Ca2+ channel blockers and potent inhibition of the delayed rectifier K+ current (IKr), by binding within the channel pore cavity upon channel gating. (The product is for research purpose only.)
References
- Ibutilide, a new compound with potent class III antiarrhythmic activity, activates a slow inward sodium current in guinea pig ventricular cells
- Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells: concentration-, time-, voltage-, and use-dependent effects
- Ibutilide (a review)
- Structural determinants of HERG channel block by clofilium and ibutilide
- Cardioversion of persistent atrial fibrillation by a combination of atrial specific and non-specific class III drugs in the goat
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.