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Published TCIMAIL newest issue No.197
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CAS RN: 69075-42-9 | Product Number: E1560
5-Ethynyluridine
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Purity: >95.0%(T)(qNMR)
Synonyms:
- 5-EU
- 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-ethynylpyrimidine-2,4(1H,3H)-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€45.00
|
Contact Us | 6 |
|
| 250MG |
€125.00
|
Contact Us | 14 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | E1560 |
| Purity / Analysis Method | >95.0%(T)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__1H__1__2N__2O__6 = 268.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 69075-42-9 |
| Reaxys Registry Number | 686532 |
| MDL Number | MFCD00876719 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(Neutralization titration) | min. 95.0 % |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 190 °C |
GHS
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Application
5-Ethynyluridine: A Clickable Form of Uridine
5-Ethynyluridine is a clickable form of uridine and can undergo azide-alkyne cycloaddition with molecules containing azide groups. It is incorporated into cellular RNA and has been used to detect transcription in vitro and in vivo.
References
- Exploring RNA transcription and turnover in vivo by using click chemistry
- Capturing the interactome of newly transcribed RNA
- Transcriptome-wide discovery of coding and noncoding RNA-binding proteins
- In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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