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CAS RN: 177355-84-9 | Product Number: D5476
DBeQ
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Purity: >98.0%(HPLC)
Synonyms:
- N,N'-Dibenzylquinazoline-2,4-diamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€203.00
|
1 | 9 |
|
| 100MG |
€623.00
|
Contact Us | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D5476 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__0N__4 = 340.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 177355-84-9 |
| Reaxys Registry Number | 7440169 |
| PubChem Substance ID | 354335589 |
| MDL Number | MFCD03691820 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 15.50 to 17.00 % |
| Melting point | 147.0 to 151.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 149 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
DBenQ: A Selective Reversible, and ATP-Competitive p97 Inhibitor
DBenQ has been reported as a selective reversible, and ATP-competitive p97 inhibitor. p97 is an important cellular AAA (ATPases associated with diverse cellular activities) ATPase, and is shown to play a critical role in the degradation of misfolded membrane and secretory proteins and also is linked to a broad array of cellular processes. Therefore, selective p97 inhibitors are valuable research tools to carry out mechanistic and cellular investigations of p97 biology.
References
- Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
- Development of p97 AAA ATPase inhibitors (a review)
PubMed Literature
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