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CAS RN: 50889-46-8 | Product Number: D5176

Dimethyl (3,3-Difluoro-2-oxoheptyl)phosphonate


Purity: >98.0%(GC)
Synonyms:
  • (3,3-Difluoro-2-oxoheptyl)phosphonic Acid Dimethyl Ester
Product Documents:
200MG
€40.00
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1G
€128.00
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Product Number D5176
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__9H__1__7F__2O__4P = 258.20 
Physical State (20 deg.C) Liquid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Moisture Sensitive
CAS RN 50889-46-8
Reaxys Registry Number 2107148
PubChem Substance ID 468591299
MDL Number

MFCD11707108

Specifications
Appearance Colorless to Light yellow clear liquid
Purity(GC) min. 98.0 %
Properties (reference)
Boiling Point 110 °C/0.4 mmHg
Flash point 136 °C
Refractive Index 1.42
GHS
Related Laws:
Transport Information:
HS Number 2931599090
Application
A Synthetic Intermediate of Prostaglandin Analogs

This product is mainly used for the synthesis of prostaglandin analogs such as lubiprostone which is a prostaglandin E1 derivative used in the treatment of chronic idiopathic constipation.

References

  • Methods of making lubiprostone and intermediates thereof
    • k. K. Kothakonda, F. Wang, B. R. Guntoori, M. T. N. Nguyen, A. P. Ceccarelli, Y. Zhao, U. Kotipalli, S. C. Duncan, K. K. Milnee, K. W. Kells, L. K. Montemayor, WO/2010/083597.
  • Prostaglandin synthesis and intermediates for use therein
    • D. ALBERICO, J. Clayton, B. I. Gorin, J. Oudenes, US 2010/0056808


Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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Other Documents

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