Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 2265-92-1 | Product Number: D3594
1,4-Difluoro-2-iodobenzene
×
![]()
×
Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
25,00 €
|
1 | 11 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D3594 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__6H__3F__2I = 239.99 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 2265-92-1 |
| Reaxys Registry Number | 2081101 |
| PubChem Substance ID | 87559832 |
| MDL Number | MFCD03094151 |
Specifications
| Appearance | Colorless to Light yellow to Light red clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 183 °C |
| Flash point | 85 °C |
| Specific Gravity (20/20) | 2.01 |
| Refractive Index | 1.56 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2903998090 |
Application
Dorsomorphin (Compound C): An Inhibitor of BMP Sinnaling and AMPK
Dorsomorphin (Compound C) is used as an inhibitor of bone morphogenetic protein (BMP) signaling, and an inhibitor of AMP-activated protein kinase (AMPK).
BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. Dorsomorphin inhibit the BMP signaling.
AMP-activated protein kinase (AMPK), a serine/threonine kinase, is an evolutionarily conserved energy sensor important for cell growth, proliferation, survival, and metabolic regulation. Dorsomorphin (Compound C) also inhibits the AMPK.
BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. Dorsomorphin inhibit the BMP signaling.
AMP-activated protein kinase (AMPK), a serine/threonine kinase, is an evolutionarily conserved energy sensor important for cell growth, proliferation, survival, and metabolic regulation. Dorsomorphin (Compound C) also inhibits the AMPK.
References
- Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
- Small-molecule dissection of BMP signaling (a review)
- Compound C inhibits hypoxic activation of HIF-1 independent of AMPK
- Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
- The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.