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CAS RN: 25122-57-0 | Product Number: C3510
Clobetasone Butyrate
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Purity: >98.0%(HPLC)
Synonyms:
- 21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-Butyrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
33,00 €
|
Contact Us | 13 |
|
| 250MG |
107,00 €
|
Contact Us | 10 |
|
| 1G |
345,00 €
|
Contact Us | 24 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3510 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__3__2ClFO__5 = 478.99 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 25122-57-0 |
| Reaxys Registry Number | 6773316 |
| PubChem Substance ID | 468591128 |
| Merck Index (14) | 2364 |
| MDL Number | MFCD00133196 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Carbon) | 63.90 to 66.50 % |
| Melting point | 177.0 to 181.0 °C |
| Specific rotation [a]20/D | +137 to +142 deg(C=1, CHCL3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 179 °C |
| Specific Rotation | 140° (C=1,CHCl3) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 246-635-9 |
| RTECS# | TU4154083 |
Transport Information:
| HS Number | 2937220000 |
Application
Clobetasone Butyrate: A Moderately Potent Topical Corticosteroid
Clobetasone butyrate is classed as a moderately potent topical corticosteroid. In clinical, it is often used for the treatment of skin disorders as a cream and an ointment. (The product is for research purpose only.)
References
- Eumovate (clobetasone butyrate 0.05%) cream: a review of clinical efficacy and safety (a review)
- Development of a tandem thin-layer chromatography-high-performance liquid chromatography method for the identification and determination of corticosteroids in cosmetic products
- Simultaneous determination of seventeen glucocorticoids residues in milk and eggs by ultra-performance liquid chromatography/electrospray tandem mass spectrometry
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