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CAS RN: 14984-68-0 | Product Number: C3038
Cloperastine Hydrochloride
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 1-[2-[(4-Chlorophenyl)(phenyl)methoxy]ethyl]piperidine Hydrochloride
- 4-Chlorobenzhydryl 2-(1-Piperidyl)ethyl Ether Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€ 41,00
|
1 | 32 |
|
| 25G |
€ 160,00
|
Contact Us | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3038 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__4ClNO·HCl = 366.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 14984-68-0 |
| Related CAS RN | 3703-76-2 |
| Reaxys Registry Number | 3762484 |
| PubChem Substance ID | 253660738 |
| Merck Index (14) | 2395 |
| MDL Number | MFCD00079012 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
Properties (reference)
| Melting Point | 152 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 239-067-8 |
| RTECS# | TM6491500 |
Transport Information:
| HS Number | 2933399990 |
Application
Cloperastine Hydrochloride: A GIRK Channels Inhibitor
Cloperastine Hydrochloride is a non-narcotic central antitussive agent with G protein-coupled inwardly rectifying K+ (GIRK) channels inhibitory effects. Recently, it has been reported GIRK channel inhibitors possess antidepressant-like action.
References
- Pharmacological and clinical overview of cloperastine in treatment of cough
- Effects of the antitussive drug cloperastine on ventricular repolarization in halothane-anesthetized Guinea pigs
- Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry
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