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CAS RN: 5728-52-9 | Product Number: B1278
4-Biphenylacetic Acid
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Felbinac
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
34,00 €
|
2 | 5 |
|
| 250G |
213,00 €
|
9 | 10 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B1278 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__2O__2 = 212.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 5728-52-9 |
| Reaxys Registry Number | 1211592 |
| PubChem Substance ID | 87564212 |
| SDBS (AIST Spectral DB) | 18547 |
| Merck Index (14) | 3316 |
| MDL Number | MFCD00004351 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 161.0 to 165.0 °C |
Properties (reference)
| Melting Point | 163 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 227-233-2 |
| RTECS# | DU8229050 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2916399090 |
Application
Felbinac: A Non-Selective Cyclooxygenase (COX) Inhibitor
Felbinac is a nonsteroidal and non-selective cyclooxygenase (COX) inhibitor which has anti-inflammatory effects. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. (The product is for research purpose only.)
References
- Multiple sites of interaction between prostaglandins and non-steroidal anti-inflammatory agents
- The pharmacology of fenbufen, 3-(4-biphenylylcarbonyl)propionic acid, and 4-biphenylacetic acid, interesting antiinflammatory-analgesic agents
- Simultaneous determination of rufloxacin, fenbufen and felbinac in human plasma by high-performance liquid chromatography
- Fluorous derivatization and fluorous-phase separation for fluorometric determination of naproxen and felbinac in human plasma
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