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CAS RN: 304896-28-4 | Product Number: A3193
AGK-2
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Purity: >97.0%(HPLC)
Synonyms:
- 2-Cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)acrylamide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
€63.00
|
1 | 32 |
|
| 25MG |
€200.00
|
Contact Us | 18 |
|
| 100MG |
€543.00
|
Contact Us | 28 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A3193 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__1__3Cl__2N__3O__2 = 434.28 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 304896-28-4 |
| Reaxys Registry Number | 20613840 |
| PubChem Substance ID | 468590165 |
| MDL Number | MFCD01909444 |
Specifications
| Appearance | White to Yellow to Yellow green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
Properties (reference)
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
AGK-2: A Specific Inhibitor of Sirtuin 2 (SIRT2)
AGK-2 is a specific inhibitor of sirtuin 2 (SIRT2), a histone deacetylase enzyme. Recent studies have indicated that AGK-2 can decrease the cell death in a cellular model of Parkinson's disease. (The product is for research purpose only.)
References
- Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease
- SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
Articles/Brochures
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