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Published TCIMAIL newest issue No.197
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CAS RN: 506-32-1 | Product Number: A0781
Arachidonic Acid
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Purity: >98.0%(GC)(T)
Synonyms:
- 5,8,11,14-Eicosatetraenoic Acid
- 5,8,11,14-Icosatetraenoic Acid
- (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
74,00 €
|
4 | ≥60 |
|
| 500MG |
253,00 €
|
5 | Contact Us |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A0781 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__0H__3__2O__2 = 304.47 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Ampule (View image), 500MG-Ampule (View image) |
| CAS RN | 506-32-1 |
| Reaxys Registry Number | 1913991 |
| PubChem Substance ID | 87562313 |
| SDBS (AIST Spectral DB) | 7566 |
| Merck Index (14) | 765 |
| MDL Number | MFCD00004417 |
Specifications
| Appearance | Colorless to Light yellow to Light orange clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Specific Gravity (20/20) | 0.92 |
| Refractive Index | 1.49 |
| Solubility in water | Insoluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 208-033-4 |
| RTECS# | CE6675000 |
Transport Information:
| HS Number | 2916199590 |
Application
Reagent for platelet aggregation model
References
- Arachidonic acid induced mortality in animals - an appropriate model for the evaluation of antithrombotic drugs?
- F. Seuter, W. D. Busse, Agents Actions Suppl. 1979, 4, 175.
- Influence of aspirin, molsidomine, trapidil, and some trapidil derivatives on arachidonic acid induced reversible thrombocyte aggregation in the rabbit
- U. Zehl, H. J. Mest, W. Förster, Biomed. Biochim. Acta. 1984, 43, 381.
Application
Reagent for acute inflammatory (ear edema) model
References
- The mouse ear inflammatory response to topical arachidonic acid
- Effect of anti-inflammatory compounds on edema formation and myeloperoxidase activity in the arachidonic acid-induced ear model in the mouse
- Inhibition of arachidonic acid-induced ear oedema as a model for assessing topical anti-inflammatory compounds
- ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model
Application
Reagents for cerebral infarction model
References
- Arachidonate-induced cerebrovascular occlusion in the rat. The role of platelets and aspirin in stroke
- The sodium arachidonate-induced cerebral infarct in the rat: a model for the study of drugs
- J. Cahn, M. G. Borzeix, J. Cereb. Blood Flow Metab. 1982, 2 Suppl 1, 74.
Application
Reagent for conjunctivitis model
References
- Effects of bromfenac sodium, non-steroidal anti-inflammatory drug, on acute ocular inflammation
- T. Ogawa, T. Sakaue, T. Terai, O. Fukiage, Nihon Ganka Gakkai Zasshi, 1995, 99, 406.
- Topical arachidonic acid: a model for screening anti-inflammatory agents
- Effects of sodium naproxen eye drops on rabbit ocular inflammation induced by sodium arachidonate
- Differential inflammatory effects of arachidonic acid on rabbit conjunctiva and iris: a possible role of lipoxygenase in the conjunctival response
- P. Bhattacherjee, P. S. Kulkarni, K. E. Eakins, Adv. Prostaglandin Thromboxane Res. 1980, 8, 1727.
PubMed Literature
Articles/Brochures
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