New Palladacycle Precatalyst

Di-μ-chlorobis(2'-amino-1,1'-biphenyl-2-yl-C,N)dipalladium(II) (1) is a palladacycle dimer formed from two aminobiphenyl-pallacycle units structurally bridged by two chlorine atoms.¹⁾ 1 is a palladacycle precatalyst and by the use of 1 with various phosphine ligands can be used as a catalyst for Suzuki-Miyaura cross-coupling.²⁾ As an example, when a catalyst prepared from 1 and 1,1'-bis(diisopropylphosphino)ferrocene (dippf) is employed, couplings of benzyloxymethyltrifluoroborate with aromatic mesyl esters successfully proceed to afford the desired coupling products.^2a)