Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 32986-56-4 | Product Number: T2503
Tobramycin
×
![]()
×
Purity: >94.0%(T)
Synonyms:
- O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$124.00
|
12 | 2 | 11 |
|
| 25G |
$495.00
|
4 | 2 | 14 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T2503 |
| Purity / Analysis Method | >94.0%(T) |
| Molecular Formula / Molecular Weight | C__1__8H__3__7N__5O__9 = 467.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 32986-56-4 |
| Reaxys Registry Number | 1357507 |
| PubChem Substance ID | 87560061 |
| Merck Index (14) | 9490 |
| MDL Number | MFCD00077885 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(Nonaqueous Titration) | min. 94.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +138.0 to +148.0 deg(C=4, H2O)(calcd.on anh.substance) |
| Water | max. 8.0 % |
Properties (reference)
| Melting Point | 178 °C |
| Specific Rotation | 143° (C=4,H2O) |
| Solubility in water | Soluble |
GHS
Related Laws:
| RTECS# | WK2100000 |
Transport Information:
| HS Number | 2941.10.5000 |
Application
RNA aptamer research
References
- Direct Selection of RNA Beacon Aptamers
- Specific binding of aminoglycoside antibiotics to RNA
Application
Tobramycin: An Aminoglycoside Antibiotic Active Against Pseudomonas Aeruginosa
Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius, and is similar in structure to gentamicin [G0383]. Tobramycin interacts with the 30s and 50s subunit of prokaryotic ribosomes, and then it inhibits bacterial growth by inhibiting protein synthesis. Tobramycin is more active than gentamicin against Pseudomonas aeruginosa and active against many gentamicin resistant strains. Recently, inhaled tobramycin is effective in treating chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. (The product is for research purpose only.)
References
- Tobramycin: a review of its antibacterial and pharmacokinetic properties and therapeutic use
- The aminoglycosides: streptomycin, kanamycin, gentamicin, tobramycin, amikacin, netilmicin, and sisomicin (a review)
- Tobramycin Inhalation Powder: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis
- Tobramycin Inhalation Powder: A Review of Its Use in the Treatment of Chronic Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.