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CAS RN: 60-82-2 | Product Number: P1966
Phloretin
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Purity: >98.0%(HPLC)
Synonyms:
- 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone
- 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$22.00
|
3 | 2 | ≥60 |
|
| 5G |
$62.00
|
8 | Contact Us | ≥60 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P1966 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__4O__5 = 274.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 60-82-2 |
| Reaxys Registry Number | 1887240 |
| PubChem Substance ID | 135727056 |
| Merck Index (14) | 7326 |
| MDL Number | MFCD00002288 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
Properties (reference)
| Melting Point | 262 °C(dec.) |
| Solubility in water | Insoluble |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
Transport Information:
| HS Number | 2914.50.3000 |
Application
Phloretin: A Dihydrochalcone with Many Interesting Biological Properties
Phloretin is a dihydrochalcone and a polyphenol, can be found in apple tree leaves. Phloretin and its glycosylated derivative (phlorizin [P0248]) have many interesting biological properties. For example, phloretin inhibits sodium glucose co-transporters (SGLTs), though the inhibition is weaker than by phlorizin. In addition, phloretin shows an antioxidant activity in peroxynitrite scavenging and the inhibition of lipid peroxidation.
References
- Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
- Effect of phloretin on the permeability of thin lipid membranes
- The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids
- Application of Directly Coupled HPLC-NMR-MS to the Identification and Confirmation of Quercetin Glycosides and Phloretin Glycosides in Apple Peel
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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