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CAS RN: 55981-09-4 | Product Number: N1031

Nitazoxanide


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
  • NTZ
Product Documents:
200MG
$83.00
1   Contact Us 4  
1G
$241.00
1   Contact Us 2  
5G
$638.00
1   1   30  

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Supplemental Product Information:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number N1031
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__2H__9N__3O__5S = 307.28 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image),  200MG-Glass Bottle with Plastic Insert (View image)
CAS RN 55981-09-4
Reaxys Registry Number 1225475
PubChem Substance ID 354333058
Merck Index (14) 6567
MDL Number

MFCD00416599

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 198.0 to 202.0 °C
Properties (reference)
Melting Point 200 °C
Maximum Absorption Wavelength 416(Phosphate buffer sol.) nm
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
RTECS# VN7830000
Transport Information:
HS Number 2934.10.2000
Application
Nitazoxanide: A Thiazolide Antiprotozoal and Antiviral Agent

Nitazoxanide is originally developed as a thiazolide antiprotozoal agent that shows excellent in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is a prodrug, and following oral administration in animals, nitazoxanide is rapidly hydrolyzed to an active metabolite, tizoxanide [T3862] (desacetyl-nitazoxanide) by esterase. The antiprotozoal activity of tizoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic energy metabolism. Recently, antiviral activity of nitazoxanide against a broad range of other RNA and DNA viruses such as hepatitis B virus, hepatitis C virus and influenza virus has been recognized in in vitro systems. Nitazoxanide is synergistic with neuraminidase inhibitors, and also inhibits the replication of a broad range of viruses. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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Life Science
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