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CAS RN: 110429-36-2 | Product Number: M2645
N-Methyl Paroxetine
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Purity: >98.0%(GC)(T)
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$95.00
|
1 | 1 | 13 |
|
| 1G |
$276.00
|
3 | Contact Us | 12 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | M2645 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__0H__2__2FNO__3 = 343.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 110429-36-2 |
| Reaxys Registry Number | 768178 |
| PubChem Substance ID | 253662337 |
| MDL Number | MFCD03788781 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 109.0 to 113.0 °C |
| Specific rotation [a]20/D | -69.0 to -89.0 deg(C=0.01, MeOH) |
Properties (reference)
| Melting Point | 111 °C |
| Specific Rotation | -70° (C=0.01,MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
Transport Information:
| HS Number | 2933.39.9200 |
Application
N-Methyl paroxetine: A Synthetic Precursor of Paroxetine
N-Methyl paroxetine is a synthetic precursor of paroxetine hydrochloride hemihydrate [P1977] which is a 5-hydroxytryptamine (5-HT) uptake inhibitor.
References
- Preparation of crystalline paroxetine hydrochloride hemihydrate for use as an antidepressant
- R. D. Barnes, M. W. Wood-Kaczmar, J. E. Richardson, I. R. Lynch, P. C. Buxton, A. D. Curzons, Eur. Pat. Appl. 1987, EP 223403 A2.
- Preparation of paroxetine from N-alkyl derivatives.
- S.-z. Wang, Y. Matsumura, Eur. Pat. Appl. 1997, EP 810225 A1.
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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