Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 74050-98-9 | Product Number: K0051
Ketanserin
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$62.00
|
1 | 1 | 9 |
|
| 1G |
$186.00
|
1 | 1 | 5 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | K0051 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__2FN__3O__3 = 395.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 74050-98-9 |
| Reaxys Registry Number | 4913068 |
| PubChem Substance ID | 253661148 |
| Merck Index (14) | 5296 |
| MDL Number | MFCD00083392 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 231.0 to 235.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 233 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 10 mg/l |
| Solubility (slightly sol. in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | VA1411190 |
Transport Information:
| HS Number | 2933.59.7000 |
Application
Ketanserin: A Selective 5-HT2a Receptor Antagonist with Weak α1-Adrenoceptor Antagonistic Activity
Ketanserin is a selective 5-HT2a receptor antagonist. 5-HT receptors can be divided into some receptor subtypes. Ketanserin is used for discrimination between 5-HT receptor subtypes. Ketanserin also has weak α1-adrenoceptor antagonistic activity which may explain its antihypertensive mechanism of action. Ketanserin inhibits the effects of serotonin on platelets, and inhibits vasoconstriction caused by the catecholamine. (The product is for research purpose only.)
References
- Ketanserin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in hypertension and peripheral vascular disease
- Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes
- Molecular modeling of serotonin, ketanserin, ritanserin and their 5-HT2C receptor interactions
- Ketanserin and spiperone as templates for novel serotonin 5-HT2A antagonists (a review)
- Serotoninergic mechanisms in hypertension. Focus on the effects of ketanserin (a review)
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.