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CAS RN: 480-19-3 | Product Number: I1068
Isorhamnetin
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Purity: >95.0%(HPLC)
Synonyms:
- 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
- 3'-Methoxy-3,4',5,7-tetrahydroxyflavone
- 3'-Methylquercetin
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$97.00
|
1 | 1 | 3 |
|
| 50MG |
$339.00
|
Contact Us | Contact Us | 14 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | I1068 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__2O__7 = 316.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 480-19-3 |
| Reaxys Registry Number | 44723 |
| PubChem Substance ID | 468592077 |
| MDL Number | MFCD00017310 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
Properties (reference)
| Maximum Absorption Wavelength | 370 nm (MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | LK9275450 |
Transport Information:
| HS Number | 2932.99.7000 |
Application
Efflux pump research
Isorhamnetin has been reported to inhibit efflux pump thereby decreasing the minimum inhibitory concentrations (MICs) of Isoniazid [I0138] against Mycobacterium.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of isoniazid susceptibility by flavonoids in Mycobacterium
- Effect of naturally occurring flavonoids on lipid peroxidation and membrane permeability transition in mitochondria
- Antioxidant activity and phenolic compounds in 32 selected herbs
- Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production inactivated macrophages
- O-methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation
- In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells
- Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD
Application
Isorhamnetin: A 3'-O-Methylated Flavonoid with Biological Activities
Isorhamnetin is a natural 3'-O-methylated flavonoid (3’-O-methylated quercetin [P0042]) that occurs in fruits and medicinal herbs. It has been investigated in its antioxidant1,2) and anti-inflammatory3,4) activity, and its influence on human cancer cells.5) (The product is for research purpose only.)
References
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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Analytical Charts
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