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CAS RN: 133454-47-4 | Product Number: I0926
Iloperidone
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25MG |
$18.00
|
Contact Us | Contact Us | 11 |
|
| 100MG |
$44.00
|
Contact Us | Contact Us | 8 |
|
| 1G |
$264.00
|
Contact Us | Contact Us | 10 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | I0926 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__7FN__2O__4 = 426.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 133454-47-4 |
| Reaxys Registry Number | 7233425 |
| PubChem Substance ID | 253662251 |
| Merck Index (14) | 4900 |
| MDL Number | MFCD00866688 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 122.0 to 126.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 124 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | KM5777850 |
Transport Information:
| HS Number | 2934.99.4400 |
Application
Iloperidone: Serotonin (5HT2A) and Dopamine D2 Receptor Antagonist
Iloperidone (HP 873) is a piperidinyl-benzisoxazole derivative, structurally related to risperidone [R0087], with mixed serotonin (5HT2A) and dopamine D2 receptor antagonist properties. Iloperidone is used as a second-generation antipsychotic agent. (The product is for research purpose only.)
References
- 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-Benzisoxazoles as D2/5-HT2 Antagonists with Potential Atypical Antipsychotic Activity: Antipsychotic Profile of Iloperidone (HP 873)
- Application of hyphenated LC/NMR and LC/MS techniques in rapid identification of in vitro and in vivo metabolites of iloperidone
- Binding of antipsychotic drugs to human brain receptors - focus on newer generation compounds
- Functional characterization of the novel antipsychotic iloperidone at human D2, D3, α2C, 5-HT6, and 5-HT1A receptors
- Iloperidone: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability, regulatory affairs, and an opinion (a review)
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
C of A & Other Certificates
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Analytical Charts
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