Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 59870-68-7 | Product Number: G0534
Glabridin
×
![]()
×
Purity: >98.0%(GC)
Synonyms:
- (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl)-1,3-benzenediol
- 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol
- (R)-4-(8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl)benzene-1,3-diol
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$375.00
|
Contact Us | Contact Us | 7 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | G0534 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__0O__4 = 324.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 59870-68-7 |
| Reaxys Registry Number | 7141956 |
| MDL Number | MFCD03427694 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 228.0 to 232.0 °C |
| Specific rotation | +8.5 to +10.5 deg(C=0.5, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 230 °C |
| Solubility (soluble in) | Ethanol |
GHS
Related Laws:
| RTECS# | CZ8937649 |
Transport Information:
| HS Number | 2932.99.9090 |
Application
Paraptosis research / Paraptosis like cell death
Reference
- Glabridin induces paraptosis-like cell death via ER stress in breast cancer cells
- Phytochemistry and biological properties of glabridin (a review)
- Pharmacological properties of glabridin (a flavonoid extracted from licorice): A comprehensive review
- Review on the Diverse Biological Effects of Glabridin
- Simultaneous extraction and separation of liquiritin, glycyrrhizic acid, and glabridin from licorice root with analytical and preparative chromatography
- Rapid RP-HPLC Method for the Quantification of Glabridin in Crude Drug and in Polyherbal Formulation
Application
Glabridin: A Prenylated Isoflavonoid with Various Biological Properties
Glabridin is a prenylated isoflavonoid specifically found in the roots of licorice (Glycyrrhiza glabra L.), and has various biological properties such as antioxidant, anti-inflammatory, anti-tumor, anti-microorganism, anti-atherogenic, energy metabolism regulator, estrogenic, neuroprotective, anti-osteoporotic, skin whitening, and GABAergic inhibition. In addition, many signaling pathways, including NF-κB, MAPK, Wnt/β-catenin, ERα/SRC-1, PI3K/AKT, and AMPK, have been implicated in the regulatory activities of glabridin. (The product is for research purpose only.)
References
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.