Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 1206711-16-1 | Product Number: D5737
DMH-1
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$218.00
|
Contact Us | Contact Us | 1 |
|
| 50MG |
$652.00
|
Contact Us | Contact Us | 20 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D5737 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__0N__4O = 380.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 1206711-16-1 |
| Reaxys Registry Number | 20934957 |
| PubChem Substance ID | 468591528 |
| MDL Number | MFCD18384963 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 176.0 to 180.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
GHS
Related Laws:
| RTECS# | VC0620000 |
Transport Information:
| HS Number | 2933.49.7000 |
Application
DMH-1: A Selective Bone Morphogenetic Protein (BMP) Receptor Inhibitor
DMH1 is a selective bone morphogenetic protein (BMP) receptor inhibitor. BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. DMH1 inhibits the BMP signaling.
References
- DMH1, a Highly Selective Small Molecule BMP Inhibitor Promotes Neurogenesis of hiPSCs: Comparison of PAX6 and SOX1 Expression during Neural Induction
- DMH1, a novel BMP small molecule inhibitor, increases cardiomyocyte progenitors and promotes cardiac differentiation in mouse embryonic stem cells
- Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.