Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 27200-12-0 | Product Number: D5464
Dihydromyricetin
×
![]()
×
Purity: >97.0%(HPLC)
Synonyms:
- (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
- Ampelopsin
- (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$177.00
|
Contact Us | Contact Us | 7 |
|
| 1G |
$485.00
|
1 | Contact Us | 35 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D5464 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__2O__8 = 320.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 27200-12-0 |
| Reaxys Registry Number | 5303758 |
| PubChem Substance ID | 468591358 |
| Merck Index (14) | 579 |
| MDL Number | MFCD00189451 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | +15.5 to +17.0 deg(C=0.9, methanol) |
Properties (reference)
| Melting Point | 248 °C |
| Specific Rotation | 16° (C=0.9,MeOH) |
| Maximum Absorption Wavelength | 293 nm (MeOH) |
GHS
Related Laws:
| RTECS# | DJ2982375 |
Transport Information:
| HS Number | 2932.99.9090 |
Application
Dihydromyricetin (Ampelopsin): A Flavonoid Component of Herbal Medicines
Dihydromyricetin (also called ampelopsin) is a flavonoid component of herbal medicines. It has been reported that dihydromyricetin has antioxidant1,2), hepatoprotective3), anti-inflammatory4,5) and anti-cancer6,7) activities. Moreover, it has been recently reported that dihydromyricetin is can be effective for the treatment of alcohol use disorders (AUDs).8) In addition, the improvement of water solubility of dihydromyricetin using polymers is reported.9) (The product is for research purpose only.)
References
- 1)Antioxidation properties and mechanism of action of dihydromyricetin from Ampelopsis grossedentata
- 2)Characterization and antioxidant activity of dihydromyricetin-lecithin complex
- 3)Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin
- 4)Suppression of Inflammatory Responses by Dihydromyricetin, a Flavonoid from Ampelopsis grossedentata, via Inhibiting the Activation of NF-κB and MAPK Signaling Pathways
- 5)Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways
- 6)Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice
- 7)Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells
- 8)Dihydromyricetin as a novel anti-alcohol intoxication medication
- 9)Improving the solubility of ampelopsin by solid dispersions and inclusion complexes
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.