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CAS RN: 36923-21-4 | Product Number: D5234
Diphenylmethyl 7β-Amino-3-cephem-4-carboxylate
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Purity: >98.0%(HPLC)
Synonyms:
- Benzhydryl (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- (6R,7R)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Benzhydryl Ester
- 7β-Amino-3-cephem-4-carboxylic Acid Diphenylmethyl Ester
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$266.00
|
1 | 1 | 6 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | D5234 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__1__8N__2O__3S = 366.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 36923-21-4 |
| Reaxys Registry Number | 1089421 |
| PubChem Substance ID | 354335316 |
| MDL Number | MFCD23701579 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 164.0 to 168.0 °C |
| Specific rotation [a]20/D | +50.0 to +55.0 deg(C=1, CHCL3) |
Properties (reference)
| Melting Point | 166 °C |
| Specific Rotation | 53° (C=1,CHCl3) |
GHS
| Pictogram |
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| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
Transport Information:
| HS Number | 2934.99.4400 |
Application
A Key Building Block for Semisynthetic Cephalosporin Antibiotics
This product is used as a key building block for semisynthetic cephalosporin antibiotics, such as ceftibuten [C3391].
References
- Synthesis and biological properties of 7β-[(Z)-2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino]-3-cephem-4-carboxylic acid (7432-S), a new oral cephem antibiotic
- Synthesis and structural-activity relationships of 7β-[(Z)-2-(2-aminothiazol-4-yl)-3-(substituted)-2-propenoylamino[-3-desacetoxymethylcephalosporins
- Studies on new catechol containing cephalosporins. II. Synthesis and structure-activity relationships of cephalosporins having a catechol moiety at the C-7 position
- The synthesis and evaluation of 2-substituted-7-(alkylidene)cephalosporin sulfones as β-lactamase inhibitors
- Ceftibuten: Development of a Commercial Process Based on Cephalosporin C. Part III. Process for the Conversion of 3-Exomethylene-7(R)-glutaroylaminocepham-4-carboxylic Acid 1(S)-Oxide to Ceftibuten
PubMed Literature
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TCIMAIL
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