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CAS RN: 77883-43-3 | Product Number: D4126
Doxazosin Mesylate
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine Methanesulfonate
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$73.00
|
2 | 1 | ≥40 |
|
| 1G |
$274.00
|
1 | Contact Us | 24 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | D4126 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__3H__2__5N__5O__5·CH__4O__3S = 547.58 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 77883-43-3 |
| Related CAS RN | 74191-85-8 |
| Reaxys Registry Number | 7791129 |
| PubChem Substance ID | 135727074 |
| MDL Number | MFCD00216023 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
Properties (reference)
| Melting Point | 269 °C |
GHS
Related Laws:
| RTECS# | TK8044000 |
Transport Information:
| HS Number | 2934.99.4400 |
Application
Autophagy research
References
- Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway
- Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing
- Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
Application
Studies of alpha1-Adrenoceptor Antagonists in Cancer Cells
References
- Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
- Anoikis induction by quinazoline based alpha1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of bcl-2
- Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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