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CAS RN: 13739-02-1 | Product Number: D4061
Diacerein
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Purity: >98.0%(HPLC)
Synonyms:
- 4,5-Diacetoxyanthraquinone-2-carboxylic Acid
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$101.00
|
1 | 1 | 1 |
|
| 5G |
$261.00
|
2 | 1 | 15 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D4061 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__1__2O__8 = 368.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 13739-02-1 |
| Reaxys Registry Number | 2184909 |
| PubChem Substance ID | 135727331 |
| SDBS (AIST Spectral DB) | 53256 |
| Merck Index (14) | 2960 |
| MDL Number | MFCD00468030 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 97.0 % |
| Melting point | 241.0 to 245.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 243 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | CB8781000 |
Transport Information:
| HS Number | 2918.30.3000 |
Application
Bone research
References
- Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling
- Diacerhein and rhein reduce the ICE-induced IL-1β and IL-18 activation in human osteoarthritic cartilage
Application
Studies on Anti-inflammatory Effect
References
- Diacerhein and rhein reduce the interleukin 1β stimulated inducible nitric oxide synthesis level and activity while stimulating cyclooxygenase-2 synthesis in human osteoarthritic chondrocytes
- J.-P. Pelletier, F. Mineau, J. C. Fernandes, N. Duval, J. Martel-Pelletier, J. Heumatology 1998, 25, 2417.
- Diacerein
- Pharmacological studies of diacerein in animal models of inflammation, arthritis and bone resorption
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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