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CAS RN: 302-22-7 | Product Number: C3116
Chlormadinone Acetate
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Purity: >97.0%(HPLC)
Synonyms:
- 17α-Acetoxy-6-chloro-6-dehydroprogesterone
- 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione Acetate
- 17α-Acetoxy-6-chloropregna-4,6-diene-3,20-dione
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$83.00
|
1 | Contact Us | Contact Us |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | C3116 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__9ClO__4 = 404.93 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 302-22-7 |
| Reaxys Registry Number | 2633614 |
| PubChem Substance ID | 253660934 |
| Merck Index (14) | 2102 |
| MDL Number | MFCD00056471 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Argentometric Titration) | min. 96.0 % |
| Melting point | 206.0 to 210.0 °C |
| Specific rotation [a]20/D | +1.0 to +3.0 deg(C=0.3, CHCl3) |
Properties (reference)
| Melting Point | 208 °C |
| Specific Rotation | 2° (C=0.3,CHCl3) |
| Maximum Absorption Wavelength | 285(EtOH) nm |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Ethanol, Ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | TU3750000 |
Transport Information:
| HS Number | 2937.23.5050 |
Application
Chlormadinone Acetate: A Derivative of Progesterone Possess Strong Progestogenic Effect
Chlormadinone acetate is a derivative of natural progesterone [P0478] that shows high affinity and activity at the progesterone receptor. Chlormadinone acetate has a strong progestogenic effect about one-third higher than that of natural progesterone. In addition, chlormadinone acetate shows moderate anti-androgenic effect than that of natural progesterone. Chlormadinone acetate is used in the treatment for prostatic hyperplasia and prostatic cancer, and in combination with ethinylestradiol (or ethynylestradiol) [E0037] in contraception. (The product is for research purpose only.)
References
- Identification and anti-androgenic activity of the metabolites of 17α-acetoxy-6-chloropregna-4,6-diene-3,20-dione (chlormadinone acetate) in the rat, rabbit, dog and man
- Progestogens with antiandrogenic properties (a review)
- Ethinylestradiol/chlormadinone acetate (a review)
- Profile of the progesterone derivative chlormadinone acetate - Pharmocodynamic properties and therapeutic applications (a review)
- Analysis of meat samples for anabolic steroids residues by liquid chromatography/tandem mass spectrometry
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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