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CAS RN: 313-67-7 | Product Number: A3599

Aristolochic Acid


Purity: >95.0%(T)(HPLC)
Synonyms:
  • TR 1736
  • 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid
Product Documents:
100MG
$300.00
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Product Number A3599
Purity / Analysis Method >95.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__1NO__7 = 341.28 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Hygroscopic,Heat Sensitive
CAS RN 313-67-7
Reaxys Registry Number 345159
MDL Number

MFCD00004996

Specifications
Appearance White to Yellow powder to crystal
Purity(HPLC) min. 95.0 area%
Purity(Neutralization titration) min. 95.0 %
NMR confirm to structure
Properties (reference)
Melting Point 278 °C
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# CF3325000
Transport Information:
UN Number (DOT-AIR) UN2811
Class (DOT-AIR) 6.1
Packing Group (TCI-A) III
HS Number 2932.99.7000
Application
Aristolochic Acid: A Carcinogenic, Mutagenic, and Nephrotoxic Phytochemical

Aristolochic acid is a carcinogenic, mutagenic, and nephrotoxic phytochemical found in the flowering plant family Aristolochiaceae, which has been widely used as a traditional herbal medicine to treat kidney and urinary problems. In 1994, Vanherweghem et al. reported that a cause of progressive interstitial fibrosis of the kidney was associated with herbs containing aristolochic acid.1) Since then, aristolochic acid has been reported to be associated with the development of progressive interstitial fibrosis of the kidney, called aristolochic acid nephropathy (AAN), and with urothelial cancer in AAN patients.2-4) (The product is for research purpose only.)

References

Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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