Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 89-57-6 | Product Number: A0317
5-Aminosalicylic Acid
×
![]()
×
Purity: >98.0%(T)
Synonyms:
- 5-Amino-2-hydroxybenzoic Acid
- Mesalamine
- Mesalazine
- 5-ASA
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$27.00
|
2 | Contact Us | ≥100 |
|
| 500G |
$208.00
|
5 | 1 | 22 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | A0317 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__7H__7NO__3 = 153.14 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 89-57-6 |
| Reaxys Registry Number | 2090421 |
| PubChem Substance ID | 87561970 |
| SDBS (AIST Spectral DB) | 3423 |
| Merck Index (14) | 5904 |
| MDL Number | MFCD00007877 |
Specifications
| Appearance | White to Gray to Brown powder to crystal |
| Purity(Neutralization titration) | min. 98.0 % |
| Solubility in HCl | almost transparency |
Properties (reference)
| Melting Point | 265 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | VO1400000 |
Transport Information:
| HS Number | 2922.50.4000 |
Application
5-Aminosalicylic Acid (5-ASA): A Gastrointestinal Anti-Inflammatory Agent
5-Aminosalicylic acid (5-ASA or mesalazine) is used as a gastrointestinal anti-inflammatory agent. Although the mechanism of action remains unknown exactly, 5-ASA has in vitro and in vivo pharmacologic effects that decrease leukotriene production, scavenge for free radicals and inhibit leukocyte chemotaxis et al. For clinical purposes, amylose, ethyl cellulose or pH-dependent polymers coated 5-ASA are developed and used for drug delivery to the intestinal tract. In addition, sulfasalazine [S0580] is a prodrug of 5-ASA. (The product is for research purpose only.)
References
- Salicylates for ulcerative colitis - their mode of action (a review)
- Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers
- 5-Aminosalicylic acid abrogates T-cell proliferation by blocking interleukin-2 production in peripheral blood mononuclear cells
- Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-γ
- Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid
- High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.
Other Documents
Related Products
![5-Aminosalicylic Acid [for Biochemical Research]](/medias/A2291.jpg?context=bWFzdGVyfHJvb3R8MzU5NTl8aW1hZ2UvanBlZ3xhRGRsTDJobE5TODRPVEk0TXpZM01ERTRNREUwTDBFeU1qa3hMbXB3Wnd8ZGM2YzMwMzE2MTFjYzUxZjE4NzhlNThlNzk3YjI2MzllNmI5MmQxMDU0YmRkMTBjZDAzODg4NTU0ODM5MmU4Nw "5-Aminosalicylic Acid [for Biochemical Research]")
5-Aminosalicylic Acid [for Biochemical Research]
| Product # | A2291 |
| CAS RN | 89-57-6 |
| Purity / Analysis Method: | >98.0%(T) |