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CAS RN: 2140-79-6 | Product Number: M2291
2'-O-Methyladenosine
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$491.00
|
1 | 1 | 5 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | M2291 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__5N__5O__4 = 281.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 2140-79-6 |
| Reaxys Registry Number | 42301 |
| PubChem Substance ID | 160871099 |
| MDL Number | MFCD00056002 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 206.0 to 210.0 °C |
| Specific rotation [a]20/D | -55.0 to -59.0 deg(C=1、H2O) |
Properties (reference)
| Melting Point | 208 °C |
| Specific Rotation | -57° (C=1,H2O) |
| Maximum Absorption Wavelength | 259(H2O) nm |
| Solubility in water | Soluble |
GHS
Related Laws:
Transport Information:
| HS Number | 2940.00.6000 |
Application
2'-O-Methylribonucleosides: Basic Reagents for RNA Biochemistry and Bioscience
References
- 1)Synthesis and evaluations of 2'-O-methylribonucleotide-RNA duplexes
- a)H. Inoue, Y. Hayase, A. Imura, S. Iwai, K. Miura, E. Ohtsuka, Nucleic Acids Res. 1987, 15, 6131.
- b)B. S. Sproat, A. I. Lamond, B. Beijer, P. Neuner, U. Ryder, Nucleic Acids Res. 1989, 17, 3373.
- c)E. A. Lesnik, C. J. Guinosso, A. M. Kawasaki, H. Sasmor, M. Zounes, L. L. Cummins, D. J. Ecker, P. D. Cook, S. M. Freier, Biochemistry 1993, 32, 7832.
- a)H. Inoue, Y. Hayase, A. Imura, S. Iwai, K. Miura, E. Ohtsuka, Nucleic Acids Res. 1987, 15, 6131.
- 2)Resistance of 2'-O-modified siRNA to degradation by nucleases
- 3)Abrogation of immune activation by 2'-O-methyl-modified ssRNA and siRNA
- 4)Inhibition of hepatitis C virus (HCV) RNA replication by 2'-O-metylcytidine
PubMed Literature
Articles/Brochures
TCIMAIL
[TCIMAIL No.156] 2'-O-Methylribonucleosides: Basic Reagents for RNA Biochemistry and BioscienceProduct Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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