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CAS RN: 624-49-7 | Product Number: F0069
Dimethyl Fumarate
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Purity: >98.0%(GC)
Synonyms:
- Fumaric Acid Dimethyl Ester
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$35.00
|
1 | 1 | 16 |
|
| 500G |
$177.00
|
2 | 1 | 14 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | F0069 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__6H__8O__4 = 144.13 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 624-49-7 |
| Reaxys Registry Number | 774590 |
| PubChem Substance ID | 87569871 |
| SDBS (AIST Spectral DB) | 1132 |
| Merck Index (14) | 4287 |
| MDL Number | MFCD00064438 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 103.0 to 105.0 °C |
Properties (reference)
| Melting Point | 104 °C |
| Boiling Point | 205 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Acetone, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H312 : Harmful in contact with skin. H315 : Causes skin irritation. H318 : Causes serious eye damage. H317 : May cause an allergic skin reaction. H401 : Toxic to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P272 : Contaminated work clothing must not be allowed out of the workplace. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
Related Laws:
| RTECS# | EM6125000 |
Transport Information:
| HS Number | 2917.19.2700 |
Application
Dimethyl Fumarate, An Immunomodulator without Significant Immunosuppression
Recently, the effects of dimethyl fumarate on neuroprotection and immunomodulation have reported. Dimethyl fumarate is thought to have immunomodulatory properties without significant immunosuppression. (The product is for research purpose only.)
References
- The antipsoriatic agent dimethylfumarate immunomodulates T-cell cytokine secretion and inhibits cytokines of the psoriatic cytokine network
- Dimethylfumarate is a potent inducer of apoptosis in human T cells
- Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
- Dimethylfumarate Induces Immunosuppression via Glutathione Depletion and Subsequent Induction of Heme Oxygenase 1
- Dimethyl fumarate for multiple sclerosis
PubMed Literature
Articles/Brochures
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Safety Data Sheet (SDS)
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Specifications
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