text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Gelieve het aantal te selecteren

γ-Secretase Inhibitor

No.162(July 2014)
D4257
DAPT (1)
DAPT (1) is a γ-secretase inhibitor and a dose-dependent reducer of brain amyloid β-peptide (Aβ) levels.1) It was also demonstrated that 1 disrupts Notch signaling indirectly.2)
Notch pathway functions during diverse developmental and physiological processes and is highly conserved throughout the animal kingdom.3) It was reported that inhibition of the Notch response by 1 resulted in enhanced neuronal differentiation in embryonic stem cell-derived embryoid bodies and the enhancement is independent on sonic hedgehog signaling.4)

References

The prices are subject to change without notice. Please confirm the newest price by our online catalog before placing an order.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.
Sessiestatus
Uw sessie verloopt over 10 minuten. Na het verlopen van de sessie word u doorgestuurd naar de startpagina. Klik op de knop om de sessie vanaf dezelfde pagina voort te zetten. minuut. Na het verlopen van de sessie word u doorgestuurd naar de startpagina. Klik op de knop om de sessie vanaf dezelfde pagina voort te zetten.

Uw sessie is verlopen. U wordt doorgestuurd naar de startpagina.