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Plant Bitter Ingredient

No.161(April 2014)
S0897
Swertiamarin (1)
The bitter principles of genus Swertia can be classified into three groups: iridoid glycosides, secoiridoid glycosides, and biphenyl glycosides.1) Swertiamarin (1) is one of secoiridoid glucosides.1) The main biosynthetic pathway of 1 in the Gentianae is a route which leads from iridodial via deoxyloganic acid or loganic acid to secoiridoids.2) It has been numerously reported that 1 shows anti-inflammatory,3) anti-hyperlipidaemic,4) anti-nociceptive,4) hepatoprotective,4) anti-diabetic5,6) effects, etc.

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