Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Merci de sélectionner la quantité
Structure Defined N-Glycans for Oligosaccharide Remodeling
No.179(November 2018)
In order to study the various physiological functions of glycans, it is very essential to use a structurally defined oligosaccharide due to the structural diversity and heterogeneity that oligosaccharides impart on the post-translational modifications furnished in protein biosynthesis. Disialyloctasaccharide (1) and Sialylglycopeptide (2) are available as homogenous glycan donors for oligosaccharide remodeling reactions.1) Illustrative of this, heterogenous non-fucosylated N-glycans bound to therapeutic antibody are replaced by the structurally defined N-glycan by the oligosaccharide remodeling reaction of N-glycan with Glycosynthase (Endo-M-N175Q) which is an endo-β-N-Acetylglucosaminidase (Endo-M) mutant.
References
The prices are subject to change without notice. Please confirm the newest price by our online catalog before placing an order.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.