Tyrosine Kinase Inhibitor

References

• 1)Tyrphostins I: Synthesis and biological activity of protein tyrosine kinase inhibitors
  • A. Gazit, P. Yaish, C. Gilon, A. Levitzki, J. Med. Chem. 1989, 32, 2344.
• 2)Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinase
  • A. Gazit, N. Osherov, I. Posner, P. Yaish, E. Poradosu, C. Gilon, A. Levitzki, J. Med. Chem. 1991, 34, 1896.
• 3)Selective inhibition of the epidermal growth factor and HER2/Neu receptors by tyrphostins
  • N. Osherov, A. Gazit, C. Gilon, A. Levitzki, J. Biol. Chem. 1993, 268, 11134.
• 4)Tyrosine kinase inhibition: An approach to drug devepolment
  • A. Levitzki, A. Gazit, Science 1995, 267, 1782.
• 5)Tyrphostin AG494 blocks Cdk2 activation
  • N. Osherov, A. Levitzki, FEBS Lett. 1997, 410, 187.

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