Published TCIMAIL newest issue No.197
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TCI offers hydroxypropyl methylcellulose (HPMC) encapsulated reagents.1,2) Our product line includes capsules for amide formation reactions (condensation reactions), Suzuki coupling reactions, which are frequently used in synthetic organic chemistry and drug discovery research, and for photoredox reactions, which have recently received a lot of attention.
Using these encapsulated reagents, you can conduct reactions immediately by adding the capsules to the solution of the starting material without weighing the reaction reagents. Additionally, a reaction-accelerating effect is expected due to the construction of a reaction field in water by HPMC.3) Our encapsulated reagents can accelerate your experiments and library construction in both experimental operations and reactions.
Our practical experimental procedures using these capsules are available on product detail pages for your reference.
Products
- R0273
- Reagents for Metallophotoredox Cross-Coupling Reactions [NiBr2(dme), [Ir[dF(CF3)ppy]2(dtbbpy)]PF6, DABCO] (HPMC encapsulated)
- R0274
- Reagents for Condensation Reactions (EDCI·HCl, HOBt·H2O) (HPMC encapsulated)
- R0275
- Reagents for Suzuki-Miyaura Cross-Coupling Reactions [Pd(dppf)Cl2·CH2Cl2, Cs2CO3] (HPMC encapsulated)
- R0294
- Reagents for Condensation Reactions (DMT-MM) (HPMC encapsulated)
- R0295
- Reagents for Condensation Reactions (HATU) (HPMC encapsulated)
- R0296
- Reagents for Condensation Reactions (1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate) (HPMC encapsulated)
Advantages
- Capsule has an outer diameter of 5 mm and a length of 14 mm and contains a preweighed amount of catalyst or reagent.
- Capsules dissolve in the reaction solution, therefore adding capsules makes it simple to carry out reactions.
- Dissolves in water, DMSO, DMF, NMP, DMAc, THF/water and dioxane/water. 1)
Applications
Metallophotoredox Cross-Coupling Reaction with R0273
You can see more information on the "Applications" tab of product detail page.
Condensation Reaction with R0274
You can see more information on the "Applications" tab of product detail page.
Suzuki-Miyaura Cross-Coupling Reaction with R0275
You can see more information on the "Applications" tab of product detail page.
Related Products
References
- 1) Reagent and Catalyst Capsules: A Chemical Delivery System for Reaction Screening and Parallel Synthesis
- 2) HPMC: A Biomass-Based Semisynthetic Sustainable Additive Enabling Clean and Fast Chemistry in Water
- 3) Hydrophobic Pockets of HPMC Enable Extremely Short Reaction Times in Water
